Molecular Farming – Plants as bioreactors

molecular_farming

In order to produce biomolecules, plants use solar energy and soil borne nutrients, thus turning into bioreactors . This efficient use of energy translates into a highly competitive technology.

Through the photosynthesis process, plants use solar energy to produce organic molecules. This basic principle constitutes the foundation of our Molecular Farming technology competitive edge.

The use of plants as bioreactors to produce enzymes and other proteins at high scale is an alternate way to an efficient, cost-effective, safe and environmentally friendly production.

The main advantages of this system (compared to traditional fermentation of bacteria, fungi, yeast, animal and insect cells) are the following:

• Low production cost

• High scale production

• Efficient use of energy

• Eco-friendly production system

• Reduced risk of exposure to human/animal pathogens

The first Molecular Farming project of INDEAR, currently underway, is the recovery of bovine chymosin expressed in seeds of safflower genetically modified to that end.

The chymosin is a bovine protease used to clot milk during the cheese production process. Safflower is an ideal crop for the use of this technology, due to the following reasons: it is fit for growth in semi-arid climates, it has low participation in the food chain and excellent biosecurity features, and it is stable under storage conditions and has high-value added bioproducts.

Molecular Farming – Plants as bioreactors

In order to produce biomolecules, plants use solar energy and soil borne nutrients, thus turning into bioreactors . This efficient use of energy translates into a highly competitive technology.

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Process engineering for the production of biomolecules

INDEAR is pioneer with its platform for production and recovery of commercial-interest proteins from safflower seeds, which implies huge challenges in terms of design and innovation of processes for the entire Engineering Team.

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